These case histories were compiled from the patient charts
of Dr. Murakami while he was in practice and still treating
for Lyme. All names have been left out to protect patient and
doctor identities.
Patient A
This patient was ill for 10 years with severe pains,
arthritis, and cognitive dysfunction. Went undiagnosed by many
specialists.
Saw Dr. Murakami in 2002 and a clinical diagnosis of
Lyme disease was made. This diagnosis was substantiated by a
test from an American lab which indicated antibodies for
Borrelia burgdorferi.
Patient was initially treated with oral antibiotics,
without too much success. Was then referred to an Infectious
Disease Specialist who gave IV-therapy for three months.
Patient then improved quite dramatically after the IV-therapy
and is now back to normal life physicially and mentally.
Patient B
This patient had been sick for seven years and had seen
many physicians in Ontario, US, and BC. Dr. Murakami first saw
patient in 1999 and a clinical diagnosis of Lyme disease and
Ehrlichiosis was made.
The medication was intially by the oral route, but there
was the constant recurrence of symptoms whenever
the medications were discontinued.
Babesiosis was suspected and this was confirmed in New York
and following the treatment with appropriate medications this
patient made a remarkable recovery to this present day.
Patient C
This patient was bitten by a tick in the Okanagan and
shortly after developed severe physical and mental
dysfunction.
After many investigations and tests Lyme disease was
confirmed at the BC Centre for Disease Control.
Patient was then referred to an Infectious Disease
Specialist, who administered one month of IV therapy. ID
specialist stated that the Lyme disease was more than
adequately treated despite the fact patient continued to have
severe pains and cognitive dysfunctions, requiring narcotics
and anti-depressants.
On the regular visits to the Infectious Disease
doctor, the patient was told that all that could be done, had
been done and any persistent symptoms was post
Lyme syndrome.
Dr. Murakami saw this patient three years after intial
therapy and then referred them to another Infectious Disease
Specialist who agreed to give the full three months of
intravenous therapy.
This patient suffered for three years of a "living hell"
and was known to have stated that suicide was considered if it
weren't for family commitments.
The patient has since returned to normal health and to work
full time and is enjoying family life again.
Patient D
This patient was ill for many years and had seen countless
specialists and doctors. Unable to work in any capacity.
Family physician ordered a test from an American
laboratory, confirming acute Lyme disease. MRI of the brain
was done which showed lesions. Follow up lesions during
treatment was indicative of increasing numbers.
Prior medications were taken orally for short periods of
time and did not improve clinical condition. Dr. Murakami
referred this patient to an Infectious Disease Specialist who
gave 30 days of IV-therapy as indicated by IDSA
Guidelines.
However, in view of the evidence indicating inadequacy of
treament from clinical signs and other investigations, the
full complement of 90 days was provided by two other
Infectious Disease doctors.
Patient has since fully recovered and has since produced a
beautiful family that was never a consideration prior.
Patient E
This patient was diagnosed with Lyme diseaes in 1985 while
in California. Was seen by many physicians and for 14 years
was never completely symptom free. Eventually had to leave
career.
Dr. Murakami first saw patient in June of 2003 and started
them on oral long-term antibiotic therapy. Since there was
only partial recovery from illness prior, patient was then
referred to and Infectious Disease Specialist who administered
six weeks of IV-therapy and subsequent oral medication was
continued for a total of 11 months.
Patient at time of this case history was off medication for
two years and was able to return to career and enjoy life
again.
Patient F
This patient was bitten by an insect in 1995 and was
diagnosed with ringworm where bite mark was.
There was a rapid deterioration of health both mentally and
physically and patient could not continue on path of research
student at their university of study.
Patient saw many specialists including three Infectious
Disease specialists and there was not one mention of Lyme
disease. Patient was eventually told it was all mental and was
prescribed prozac under the supervision of a psychiatrist.
Dr. Murakami first saw patient in March 2002 and intiated
oral antibiotics and since there was minimal limited response
the intravenous route was advised.
Was referred to an Infectious Disease Specialist who gave
six weeks of IV-therapy with moderate improvement in 2002.
Another Infectious Disease doctor gave further eight weeks of
IV-therapy with some benefit.
Patient did have some improvement with quality of life and
was able to do more activities and recently was able to start
a family.
Patient G
This patient was bitten by an insect in 2003 in Holland and
developed severe mental and physical discomfort and
dysfunction.
Patient was seen by Dr. Murakami in 2004 and a clinical
diagnosis of Lyme disease was made and as well a clinical
diagnosis of Babesiosis.
The response to oral medications was excellent initially,
but there was a deterioration of symptoms. Patient was then
referred to an Infectious Disease Specialist who ordered IV
medications which helped considerably.
The suspicion of Babesiosis was treated appropriately with
medications and patient made a complete recovery. Patient has
now been off medications for 4 years (at time of case
history).
Patient H
Patient was infected in California in 1992 after a tick
bite. Was unable to continue working in profession and was on
disability pension.
There had been many specialists who had seen this patient,
including Infectious Disease doctors, Neurologists,
Endocrinologists, Ophthalmologists and other
physicians.
Patient was seen by Dr. Murakami in August 2003 and a
clinical diagnosis of Lyme disease was made. Oral antibiotics
were initiated and since there was very little response,
patient was referred to an Infectious Disease specialist who
administered IV-therapy for three months. Patient recovered
rapidly and was enjoying better quality of life and was
looking forward to returning to their profession. (at time of
case history)
Patient I
This patient was from Edmonton and had many problems.
Patient was investigated by University Hospital with no
definitive diagnosis being made, after complete and thorough
testing.
Dr. Murakami saw patient in 2003 and multiple tests were
ordered, including tests for the co-infections of Lyme
disease.
Rocky Mountain Spotted Fever and Bartonella came back
positive indicating an old past infection.
A clinical diagnosis of Lyme disease was made and
medications were initiated orally in combinations of
antibiotics.
With help of a specialist in Edmonton, the patient was
given prolonged antibiotics and steadily improved.
Patient recently attended Dr. Murakami's retirement party
and was not recognized as the improvement was very
dramatic.
Patient J
This patient was from Alaska and was disabled with severe
fatigue, arthritis and cognitive dysfunction for over the last
20 years of their life. Many specialists and no definitive
diagnosis was established, despite all the investigations
conducted.
This patient saw Dr. Murakami in 2006 in Vancouver and a
diagnosis of Lyme disease and subsequent Babesiosis was
made.
With the cooperation of the patient's family physician,
medications were initiated for both of these conditions and
patient had a prolonged but successful improvement with major
increase in all mental and physical activities.
Patient was off all medications since January 2008 without
any recurrence of symptoms.
Patient K
This patient was a medical professor at a Canadian
university and was severely disabled for over three years. Was
seen by many specialists in Toronto, Ontario.
Patient was incapacitated both mentally and physically and
was confined to a wheelchair when Dr. Murakami saw them in
March 2007.
Patient's tests were negative for Lyme in Canada, but
positive from a State Health Board approved laboratory in the
USA.
A clinical diagnosis of Lyme disease was made and oral
antibiotics were prescribed. After five weeks of antibiotic
therapy the patient was able to walk again.
After 3 months the patient was able to carry on
conversation and multi-task, which was completely impossible
prior to therapy.
Dr. Murakami saw the patient the spring of 2008 and looked
the picture of health.
Patient L
This patient was working when they suddenly experienced
general debility and poor health in 1999.
Patient was seen by many physicians and no diagnosis was
established. All hope of living a normal life was abandoned by
this patient as they were told they had only a few years left
to live.
Patient was seen by Dr. Murakami in April 2008 and the
diagnosis of clinical Lyme disease was made. An equivocal test
from the government approved USA lab helped to confirm the
diagnosis..
Quality of life was very poor and there was desperation in
the request to have therapy as soon as possible. This was
initiated.
Dramatic improvement in conditions were seen after 7 months
of therapy and patient stated they felt 95% better.
Patient did not restart medications and improvement has
continued to be gradual.